Trajectory inference

Mapping lineage-traced cells across time points with moslin
Simultaneous profiling of single-cell gene expression and lineage history holds enormous potential for studying cellular …
Marius Lange, Zoe Piran, Michal Klein, Bastiaan Spanjaard, Dominik Klein, Jan Philipp Junker, Fabian J. Theis, Mor Nitzan
Code DOI
Mapping lineage-traced cells across time points with moslin
Modeling dynamical biological processes through the lens of single-cell genomics
Cells dynamically change their molecular state in many situations. Single-cell assays allow us to describe this state with …
Marius Lange
PDF TUM online library
Modeling dynamical biological processes through the lens of single-cell genomics
CellRank for directed single-cell fate mapping
Computational trajectory inference enables the reconstruction of cell state dynamics from single-cell RNA sequencing experiments. …
Marius Lange, Volker Bergen, Michal Klein, Manu Setty, Bernhard Reuter, Mostafa Bakhti, Heiko Lickert, Meshal Ansari, Janine Schniering, Herbert B Schiller, Dana Pe’er, Fabian J Theis
Code DOI
CellRank for directed single-cell fate mapping
Mapping lineage-traced single-cells across time-points
Simultaneous profiling of single-cell gene expression and lineage history holds enormous potential for studying cellular decision …
Marius Lange, Zoe Piran, Michal Klein, Fabian J. Theis, Mor Nitzan
PDF
Mapping lineage-traced single-cells across time-points
Mapping lineage-traced single cells across time points (NeurIPS LMRL)
Simultaneous profiling of single-cell gene expression and lineage history holds enormous potential for studying cellular decision …
Dec 3, 2021 4:35 PM — Dec 2, 2021 11:00 PM NeurIPS Learning Meaningful Representations of Life (LMRL)
Marius Lange
Mapping lineage-traced single cells across time points (NeurIPS LMRL)
CellRank for directed single-cell fate mapping (ISMB/ECCB)
Computational trajectory inference enables the reconstruction of cell state dynamics from single-cell RNA sequencing experiments. …
Jul 12, 2021 4:00 PM — Jul 11, 2021 10:00 PM ISMB/ECCB
Marius Lange
CellRank for directed single-cell fate mapping (ISMB/ECCB)
Generalizing RNA velocity to transient cell states through dynamical modeling
RNA velocity has opened up new ways of studying cellular differentiation in single-cell RNA-sequencing data. It describes the rate of …
Volker Bergen, Marius Lange, Stefan Peidli, F Alexander Wolf, Fabian J Theis
Code DOI
Generalizing RNA velocity to transient cell states through dynamical modeling
Concepts and limitations for learning developmental trajectories from single cell genomics
Single cell genomics has become a popular approach to uncover the cellular heterogeneity of progenitor and terminally differentiated …
Sophie Tritschler, Maren Büttner, David S Fischer, Marius Lange, Volker Bergen, Heiko Lickert, Fabian J Theis
DOI
Concepts and limitations for learning developmental trajectories from single cell genomics
scSLAM-seq reveals core features of transcription dynamics in single cells
Single-cell RNA sequencing (scRNA-seq) has highlighted the important role of intercellular heterogeneity in phenotype variability in …
Florian Erhard, Marisa A. P. Baptista, Tobias Krammer, Thomas Hennig, Marius Lange, Panagiota Arampatzi, Christopher S. Jürges, Fabian J. Theis, Antoine-Emmanuel Saliba, Lars Dölken
DOI
scSLAM-seq reveals core features of transcription dynamics in single cells