Marius Lange
Incoming Faculty (University of Basel)
Department of Biomedicine & BRCCH, University of Basel (from 2027)
Treutlein Lab, D-BSSE, ETH Zürich
In January 2027, I will start as Tenure-Track Assistant Professor in Systems Developmental Medicine at the University of Basel, in a joint appointment between the Department of Biomedicine (DBM) and the Basel Research Centre for Child Health (BRCCH). I am currently recruiting PhD students and postdocs.
Until then, I am a postdoctoral researcher in the lab of Barbara Treutlein at ETH Zürich (Department of Biosystems Science and Engineering), co-supervised by Dana Pe’er at MSKCC (Computational and Systems Biology Program), and an associated researcher at ETH’s AI Center.
In my research, I focus on understanding dynamical biological processes through the lens of single-cell genomics. To this end, I develop computational tools and apply them to solve biological questions that arise in processes including development, regeneration and reprogramming. In my postdoc, I’m particularly interested in studying the development of the human brain in organoid model systems, integrating spatio-temporal data across molecular modalities to understand regulatory relationships. In Basel, my group will extend this work to organ maturation in childhood, building age-specific molecular references that make it possible to tell healthy developmental trajectories apart from the earliest signs of disease.
I have received multiple awards, grants, and scholarships, including the Helmholtz Software Award, the Rainer-Rudolph Prize, an Otto Bayer Fellowship, a Joachim-Herz Add-On Fellowship and an EMBO Postdoc Fellowship (2023–2025).
Previously, I completed my PhD in Computational Biology (summa cum laude) in the group of Fabian Theis at Helmholtz Munich/Technical University of Munich (TUM), where I co-developed CellRank and moscot. Both tools are used by biologists around the world to gain deeper understandings into the factors that drive cell fate decisions in health and disease.
Interests#
- Generative modeling
- Single-cell and spatial genomics
- Organoids
- Human development & disease
- Developmental medicine & child health
Education & Experience#
- Tenure-Track Assistant Professor in Systems Developmental Medicine — University of Basel (DBM & BRCCH), from 2027
- Postdoc in Computational Biology — ETH Zürich & MSKCC, New York, 2023–2026
- PhD in Computational Biology — Technical University of Munich, 2023
- MSc in Applied Mathematics — University of Oxford, 2017
- BSc in Physics — University of Freiburg, 2016